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Factory For Trimecaine Hydrochloride - 87-90-1, symclosene – Dumi

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Factory For Trimecaine Hydrochloride - 87-90-1, symclosene – Dumi Detail:

Names

Name 1,3,5-trichloro-1,3,5-triazinane-2,4,6-trione
Synonym More Synonyms

 Chemical & Physical Properties

Density 2.2±0.1 g/cm3
Boiling Point 272.3±23.0 °C at 760 mmHg
Melting Point 249-251 °C(lit.)
Molecular Formula C3Cl3N3O3
Molecular Weight 232.409
Flash Point 118.5±22.6 °C
Exact Mass 230.900528
PSA 66.00000
LogP 0.11
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.686
Stability Stable. Hygroscopic, and may decompose in contact with moisture. Contact with combustible material may lead to fire. Incompatible with acids, reducing agents, water, strong oxidizing agents.
Water Solubility 1.2 g/100mL (25 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XZ1925000
CHEMICAL NAME :
s-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-trichloro-
CAS REGISTRY NUMBER :
87-90-1
BEILSTEIN REFERENCE NO. :
0202022
LAST UPDATED :
199710
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C3-Cl3-N3-O3
MOLECULAR WEIGHT :
232.41
WISWESSER LINE NOTATION :
T6NVNVNVJ AG CG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent – rabbit
REFERENCE :
28ZPAK “Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku,” Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972 Volume(issue)/page/year: -,153,1972
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent – rabbit
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570617 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LDLo – Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
3570 mg/kg
TOXIC EFFECTS :
Gastrointestinal – ulceration or bleeding from stomach
REFERENCE :
34ZIAG “Toxicology of Drugs and Chemicals,” Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,167,1969
TYPE OF TEST :
LD50 – Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent – rat
DOSE/DURATION :
406 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 42,417,1977
TYPE OF TEST :
LC – Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent – rat
DOSE/DURATION :
>2 gm/m3/1H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MONS** Monsanto Co. Toxicity Information. (Monsanto Industrial Chemicals Co., Bancroft Bldg., Suite 204, 3411 Silverside Rd., Wilmington, DE 19810) Volume(issue)/page/year: -,-,1972
TYPE OF TEST :
LDLo – Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent – rabbit
DOSE/DURATION :
1900 mg/kg
TOXIC EFFECTS :
Behavioral – coma
REFERENCE :
MONS** Monsanto Co. Toxicity Information. (Monsanto Industrial Chemicals Co., Bancroft Bldg., Suite 204, 3411 Silverside Rd., Wilmington, DE 19810) Volume(issue)/page/year: -,-,1972
TYPE OF TEST :
LDLo – Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent – rabbit
DOSE/DURATION :
5010 mg/kg
TOXIC EFFECTS :
Behavioral – somnolence (general depressed activity) Behavioral – food intake (animal) Liver – other changes
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570617
TYPE OF TEST :
LD50 – Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal – species unspecified
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 31,959,1980 *** REVIEWS *** TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 69,287,1986 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS – National Occupational Hazard Survey (1974) NOHS Hazard Code – 84386 No. of Facilities: 5356 (estimated) No. of Industries: 17 No. of Occupations: 12 No. of Employees: 19489 (estimated) NOES – National Occupational Exposure Survey (1983) NOES Hazard Code – 84386 No. of Facilities: 9856 (estimated) No. of Industries: 93 No. of Occupations: 67 No. of Employees: 171094 (estimated) No. of Female Employees: 73008 (estimated)

 Safety Information

Symbol GHS03 GHS07 GHS09
GHS03, GHS07, GHS09
Signal Word Danger
Hazard Statements H272-H302-H315-H319-H335-H410
Supplemental HS Contact with acids liberates toxic gas.
Precautionary Statements P210-P273-P280-P305 + P351 + P338-P370 + P378-P501
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes Xn:Harmful
Risk Phrases R22;R31;R36/37;R50/53;R8
Safety Phrases S8-S26-S41-S60-S61
RIDADR UN 2468 5.1/PG 2
WGK Germany 2
RTECS XZ1925000
Packaging Group II
Hazard Class 5.1
HS Code 2933692200

 Synthetic Route

Previous 1/3 Next

Tricyanic acid structure

Tricyanic acid

CAS#:108-80-5

~%

symclosene Structure

symclosene

CAS#:87-90-1

Literature: Journal of the Society of Chemical Industry, London, , vol. 67, p. 66 US2969360 , ; Yuki Gosei Kagaku Kyokaishi, , vol. 15, p. 241,243 Chem.Abstr., , p. 12107 Yuki Gosei Kagaku Kyokaishi, , vol. 15, p. 35,36, 38 Chem.Abstr., , p. 10454
1,3-dichloro-1,3-diazetidine-2,4-dione structure

1,3-dichloro-1,…

CAS#:24604-62-4

~%

symclosene Structure

symclosene

CAS#:87-90-1

Literature: Monatshefte fuer Chemie, , vol. 101, p. 264,271,273 C: MVol.D3, 5.5, page 144 – 145
chloroimino(oxo)methane structure

chloroimino(oxo…

CAS#:13858-09-8

~%

N/A structure

N/A

CAS#:26231-96-9

symclosene Structure

symclosene

CAS#:87-90-1

Literature: Monatshefte fuer Chemie, , vol. 102, p. 127 C: MVol.D3, 5.2.4, page 141 – 142

 Customs

HS Code 2933692200
Summary 2933692200 1,3,5-trichloro-1,3,5-triazinane-2,4,6-trione。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

 Articles11

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P2X7R activation drives distinct IL-1 responses in dendritic cells compared to macrophages.

Cytokine 74 , 293-304, (2015)

The P2X(7)R is a functionally distinct member of the P2X family of non-selective cation channels associated with rapid activation of the inflammasome complex and signalling interleukin (IL)-1β release…

Halonium ion mediated synthesis of 2-halomethylene-3-oxoketoxime derivatives from isoxazoline N-oxides.

J. Org. Chem. 78(17) , 8872-9, (2013)

A protocol for the N-bromosuccinimide (NBS)- and trichloroisocyanuric acid (TCCA)-mediated synthesis of novel 2-halomethylene-3-oxoketoximes via one-pot halogenation/oxidation of isoxazoline N-oxide d…

Stability and toxicity of selected chlorinated benzophenone-type UV filters in waters.

Acta Chim. Slov. 60(4) , 826-32, (2013)

In our study, the transformation of two most widely used UV filters, benzophenone-3 (BP3) and benzophenone-4 (BP4), in chlorinated water with disinfection reagents sodium hypochlorite (NaClO) and tric…

 Synonyms

MFCD00006553
symclosene
EINECS 201-782-8
Trichloroisocyanuric Acid

 

 

 

 

Names

Name 1,3,5-trichloro-1,3,5-triazinane-2,4,6-trione
Synonym More Synonyms

 Chemical & Physical Properties

Density 2.2±0.1 g/cm3
Boiling Point 272.3±23.0 °C at 760 mmHg
Melting Point 249-251 °C(lit.)
Molecular Formula C3Cl3N3O3
Molecular Weight 232.409
Flash Point 118.5±22.6 °C
Exact Mass 230.900528
PSA 66.00000
LogP 0.11
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.686
Stability Stable. Hygroscopic, and may decompose in contact with moisture. Contact with combustible material may lead to fire. Incompatible with acids, reducing agents, water, strong oxidizing agents.
Water Solubility 1.2 g/100mL (25 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XZ1925000
CHEMICAL NAME :
s-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-trichloro-
CAS REGISTRY NUMBER :
87-90-1
BEILSTEIN REFERENCE NO. :
0202022
LAST UPDATED :
199710
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C3-Cl3-N3-O3
MOLECULAR WEIGHT :
232.41
WISWESSER LINE NOTATION :
T6NVNVNVJ AG CG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent – rabbit
REFERENCE :
28ZPAK “Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku,” Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972 Volume(issue)/page/year: -,153,1972
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent – rabbit
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570617 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LDLo – Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
3570 mg/kg
TOXIC EFFECTS :
Gastrointestinal – ulceration or bleeding from stomach
REFERENCE :
34ZIAG “Toxicology of Drugs and Chemicals,” Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,167,1969
TYPE OF TEST :
LD50 – Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent – rat
DOSE/DURATION :
406 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 42,417,1977
TYPE OF TEST :
LC – Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent – rat
DOSE/DURATION :
>2 gm/m3/1H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MONS** Monsanto Co. Toxicity Information. (Monsanto Industrial Chemicals Co., Bancroft Bldg., Suite 204, 3411 Silverside Rd., Wilmington, DE 19810) Volume(issue)/page/year: -,-,1972
TYPE OF TEST :
LDLo – Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent – rabbit
DOSE/DURATION :
1900 mg/kg
TOXIC EFFECTS :
Behavioral – coma
REFERENCE :
MONS** Monsanto Co. Toxicity Information. (Monsanto Industrial Chemicals Co., Bancroft Bldg., Suite 204, 3411 Silverside Rd., Wilmington, DE 19810) Volume(issue)/page/year: -,-,1972
TYPE OF TEST :
LDLo – Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent – rabbit
DOSE/DURATION :
5010 mg/kg
TOXIC EFFECTS :
Behavioral – somnolence (general depressed activity) Behavioral – food intake (animal) Liver – other changes
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570617
TYPE OF TEST :
LD50 – Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal – species unspecified
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 31,959,1980 *** REVIEWS *** TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 69,287,1986 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS – National Occupational Hazard Survey (1974) NOHS Hazard Code – 84386 No. of Facilities: 5356 (estimated) No. of Industries: 17 No. of Occupations: 12 No. of Employees: 19489 (estimated) NOES – National Occupational Exposure Survey (1983) NOES Hazard Code – 84386 No. of Facilities: 9856 (estimated) No. of Industries: 93 No. of Occupations: 67 No. of Employees: 171094 (estimated) No. of Female Employees: 73008 (estimated)

 Safety Information

Symbol GHS03 GHS07 GHS09
GHS03, GHS07, GHS09
Signal Word Danger
Hazard Statements H272-H302-H315-H319-H335-H410
Supplemental HS Contact with acids liberates toxic gas.
Precautionary Statements P210-P273-P280-P305 + P351 + P338-P370 + P378-P501
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes Xn:Harmful
Risk Phrases R22;R31;R36/37;R50/53;R8
Safety Phrases S8-S26-S41-S60-S61
RIDADR UN 2468 5.1/PG 2
WGK Germany 2
RTECS XZ1925000
Packaging Group II
Hazard Class 5.1
HS Code 2933692200

 Synthetic Route

Previous 1/3 Next

Tricyanic acid structure

Tricyanic acid

CAS#:108-80-5

~%

symclosene Structure

symclosene

CAS#:87-90-1

Literature: Journal of the Society of Chemical Industry, London, , vol. 67, p. 66 US2969360 , ; Yuki Gosei Kagaku Kyokaishi, , vol. 15, p. 241,243 Chem.Abstr., , p. 12107 Yuki Gosei Kagaku Kyokaishi, , vol. 15, p. 35,36, 38 Chem.Abstr., , p. 10454
1,3-dichloro-1,3-diazetidine-2,4-dione structure

1,3-dichloro-1,…

CAS#:24604-62-4

~%

symclosene Structure

symclosene

CAS#:87-90-1

Literature: Monatshefte fuer Chemie, , vol. 101, p. 264,271,273 C: MVol.D3, 5.5, page 144 – 145
chloroimino(oxo)methane structure

chloroimino(oxo…

CAS#:13858-09-8

~%

N/A structure

N/A

CAS#:26231-96-9

symclosene Structure

symclosene

CAS#:87-90-1

Literature: Monatshefte fuer Chemie, , vol. 102, p. 127 C: MVol.D3, 5.2.4, page 141 – 142

 Customs

HS Code 2933692200
Summary 2933692200 1,3,5-trichloro-1,3,5-triazinane-2,4,6-trione。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

 Articles11

More Articles

P2X7R activation drives distinct IL-1 responses in dendritic cells compared to macrophages.

Cytokine 74 , 293-304, (2015)

The P2X(7)R is a functionally distinct member of the P2X family of non-selective cation channels associated with rapid activation of the inflammasome complex and signalling interleukin (IL)-1β release…

Halonium ion mediated synthesis of 2-halomethylene-3-oxoketoxime derivatives from isoxazoline N-oxides.

J. Org. Chem. 78(17) , 8872-9, (2013)

A protocol for the N-bromosuccinimide (NBS)- and trichloroisocyanuric acid (TCCA)-mediated synthesis of novel 2-halomethylene-3-oxoketoximes via one-pot halogenation/oxidation of isoxazoline N-oxide d…

Stability and toxicity of selected chlorinated benzophenone-type UV filters in waters.

Acta Chim. Slov. 60(4) , 826-32, (2013)

In our study, the transformation of two most widely used UV filters, benzophenone-3 (BP3) and benzophenone-4 (BP4), in chlorinated water with disinfection reagents sodium hypochlorite (NaClO) and tric…

 Synonyms

MFCD00006553
symclosene
EINECS 201-782-8
Trichloroisocyanuric Acid

Product detail pictures:

Factory For Trimecaine Hydrochloride - 87-90-1, symclosene – Dumi detail pictures

Factory For Trimecaine Hydrochloride - 87-90-1, symclosene – Dumi detail pictures


Related Product Guide:

All we do is usually affiliated with our tenet " Buyer to start with, Belief to start with, devoting about the food packaging and environmental defense for Factory For Trimecaine Hydrochloride - 87-90-1, symclosene – Dumi , The product will supply to all over the world, such as: Indonesia, Russia, United States, Due to our good products and services, we have received good reputation and credibility from local and international customers. If you need more information and are interested in any of our products, please feel free to contact us. We look forward to becoming your supplier in the near future.

contact us:

skype/wechat/whatsapp :+8617172178866
e-mail:victoria@chinadumi.com

 

 

Packing

gfhdfh (2)

 

Why Choose US?
1. Selecting raw materials strictly,our products are the highest purity.
2.Reasonable and competitive price. Provide the best and professional service.
3.Fast delivery of the samples ,samples from stock. Reliable shipping way.
4.Full experience of large numbers containers loading in Chinese sea port.
5. Best after-service after shipment .
6. Professional documents for your custom clearance.

 

1.How can we guarantee quality?
Always a pre-production sample before mass production; Always final Inspection before shipment.
2.why should you buy from us ?
(1)High purity good quality with pretty competitive price. (2)Large capacity of stable products supply. (3)Safty and fast shipment by sea/by air. (4)Sample order acceptable.(5)Good and tight packing as customized.
3.What’s your MOQ? What is the time of shipment?
Normally,our MOQ is 1kg. But it could be according to your actual demand. Any quantity is OK.
Generally 2-3 days after receiving the payment (except Chinese holidays)
4.Is there a discount?
Of course, we will consider a discount for first time purchasers, even for large quantities.
5.what payment terms do you accept ? we’d like to accept bank transfer, Western Union or BTC.

  • We feel easy to cooperate with this company, the supplier is very responsible, thanks.There will be more in-depth cooperation.
    5 Stars By Aurora from Rwanda - 2018.11.11 19:52
    The manufacturer gave us a big discount under the premise of ensuring the quality of products, thank you very much, we will select this company again.
    5 Stars By Marcia from Armenia - 2018.02.12 14:52
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